back to established heuristics
first heruistic-->
one super card works better than any 2 video cards in SLI costing 1/2 as much as the super card
therefore
one super card will work better than any 4 video cards in SLI costing 1/4 as much as the super card
second established heruistic ->
SLI/Crossfire only useful if you have super duper uber resolution monitor(s)
so to use quad SLI/Crossfire you would need a display that would make Darpa green with envy
Fonger, what do you mean by a "super card". Unless you are talking Firepro or Quadro you will not outperform a crossfire or sli combination with a single card unless you are making a ridiculous comparison like Sli cuda based Nvida cards vs a 6990 6gb card. As for the price of a workstation card, it far surpass gaming price/performance ratio as that isn't the intent of such a card. Or, if by super cards you mean dual gpu cards than they are not better performance wise, and most certainly are not half the price. If you crossfire 2 HD 6970 2gb cards you will get more performance than one 6990 4gb card, and will probably only around 25-35% more. Sli/Crossfire are not only for larger display either. The extra vram which comes with having 2 cards allows for you to handle higher resolutions much better as well as give the ability for proper multi monitor support, but the performance of crossfire is still better on a regular sized monitor. You don't loose performance if you are running it on a regular monitor, the card just isn't worked nearly enough.
A comparison chart with 6970 crossfire and 6990 4gb from "hardwarecanucks" :

And as for pricing (newegg), a "GIGABYTE" HD 6970 is around Now: $349.99 (x2 would come to $700+tax)
a "GIGABYTE" HD 6990 4gb is $739.99, so the pricing is around the same.
I am slightly confused as to what point you are stating. The only negative to crossfire and sli over a dual gpu card is the extra heat generated, but if you are putting multiple cards in your computer it would be assumed that you know about the temps generated.
Anyway, like I said before... Have a great time building your super machine Thor. Make sure you post up a picture of what the insides look like while its shiny and new, and let me know some benchmarks

(or at least the fps in some of your games

).