i have replaced the Translate_ENGLISH.txt but it is still messed up with the
#FFFFF can somone help please or give me a new file to override.
I had the same problem.
It started with the "Legendary" patch. To be honest i tried A LOT of things to make it right.
Last day Steam downloaded something for Skyrim and Taa-daa...
Everything works 
I suggest being patient. It should "fix itself" after some time.
Yeah, the .txt file didn't work for me either.
I've been verifying cache everyday at night. No changes.
I'll be patient.
Ok try making sure you have
Skyrim_English.DLSTRINGS
Skyrim_English.ILSTRINGS
Skyrim_English.STRINGS
Update_English.DLSTRINGS
Update_English.ILSTRINGS
Update_English.STRINGS
In your Data\strings folder. If not download FOMM (Fallout mod manager) from the New Vegas Nexus (or any program that can extract bsa files) start up FOMM, go to tools, open BSA browser, open and extract strings\ of Skyrim - Interface.bsa and Update.bsa. If that doesn't do it I'm out of tricks.