Yeah, some of the menu options are screwed. I am playing Survival, but luckily with a mod that gives me the normal save function. For quitting I just use Alt + F4
https://drive.google.com/open?id=0B74_xtpPgnoRS0U1NEN5T3AtWm8 If you've downloaded the Fallout 4 EXE file from Crimsomrider to continue playing with the old version of Fallout 4 that supports F4SE but you're missing the .dll, here's your fix!
I have the bug with the NPCs not responding as well, they only "react" if I stand on a certain side of them, so I have to walk around them trying to talk to them, until it works, it's really annoying. Was there ever a fix to this issue?