Are controllers compatible with all mods?

[javirod800]

Hey everyone. I'm very new to modding, but I wanted to know if controllers are a viable option when playing a heavily modded single player game. I have a list of 50+ mods I'm planning to install (most are minor gameplay enhancements so I'm hoping my PC can run them all) and I'm not entirely sure if controller inputs will be able to function with all of them. I know that some mods are fully compatible with a controller, but if I can't efficiently manage all my mods with a controller I'd rather just play the game with a keyboard and mouse from the get go and spare myself the headache.