A few human leaders may have been turned into Darkspawn by the Maker, if the Chantry isn't full of it (and we get plenty of hints that the Chantry might be full of it; at the least, we know that their leaders can be arogant, selfish, corupt, and political whores). If I were a human in the Dragon Age setting, let alone a Dwarf or Elf, I wouldn't see that as making me in any way responsible for the creation of the Dark Spawn. Even if it did, I wouldn't see that responsibility as obligating me to let women be kidnapped and forced to become Brood Mothers, or obligating me to let the Dark Spawn kill off most of my species.
That said, the sins of the fathers passing onto their sons is one of the oldest religious arguments, and it's fun to see the Bioware writers playing with it.
The Architect is an easy character to feel sympathy for, and from his point of view he's doing the best he can for his people. Unfortunately his plan for "peaceful co-existence" requires genocide. Passing that off as "hard choices" is sophistry.