If SE fails to start BEFORE getting to the main menu and you use a laptop(with Nvidia), try this:

[EveningTide]

If you have a gaming laptop, it's likely you have two graphic processors. One for display and another that is used as a rendering engine.

 

If you have a Nvidia processor, then you need to go into the Nvidia control panel, go to "Manage 3D settings" and then head to "Program Settings".

 

It'll take a bit to load.

 

You should see a drop down and buttons next to it. From the scroll down, look for Skyrim SE executable, then click "Add".

 

Now go to the section below that says:

 

2. Select preferred graphics processor for this program:

 

Here you need to select your Nvidia processor because it'll be your integrated gpu by default.

 

Repeat the above for the Skyrim Special Edition Launcher executable as well. This will enable it to redetect your GPU.

This is what causes SE to max your CPU out and crash as the integrated processor is trying to load a program way too powerful for it.

 

 

[EveningTide]

I also run Windows 10, so I can say this is not an OS issue.

[SMB92]

Thanx for posting this. Also to be on the safe side, be sure to select "prefer maximum power" if it offers you this.