I totally agree - my uninstallation "attempt" was a less than stellar brain-fart. Missing textures would definitely be the culprit as a result. In fact, it was so bad that all my saves became immediately corrupted to the point that the game refused to load them. And then ..... and this is the weird part - that whole game simply disappeared and it reverted back to my previous game (the one I had initially replaced) and my primary NPC's are fine - and everything looks grand - added NPC's via mods still have that crazy body skin texture, but nothing is purple! lol I can simply disable the various mod plug-ins for these added in NPC's if it bothers me too much.
If I DO however, change my follower females bodies using AFT, it gives them that same messed up texture, but I have a mod that provides a craftable "NudeClean" thing I can give them like a clothing item and equip them with which does as it says, and cleans up the texture back to what it should be. With this done I can clothe them in shorts and not see that crazed texture on exposed legs and arms. In a nutshell, I have the game working - missions function, scenery looks great - don't try to fix what ain't broken this time around. I have certain things in the L.O. set, and I don't allow anything to change their position, as it seems that the smallest inadverdant change can ruin a game.
Live and learn, as they say.
I guess that now - and am happy to say - my one big issue is the amount of "junk" modders put into their added buildings, grounds etc - I am OCD in RL and cannot abide "clutter" so I used to spend hours scrapping and cleaning settlements just to rid my game of the crap Bethesda seems to feel is needed to add their version of an "immersive" touch. Finding all those tiny "fuses" laying about, or single, un-boxed rounds - what a pain the arse! lol This is why I have every "Clean and Smooth" mod installed - the author of these mods does a great job, and saves me hours of work at each settlement. So I find a real cool New Location type mod that gives us a real nice new piece of real estate, with maybe a whole town, some added NPC action, and maybe a lore-friendly quest to go with it, and I download/install it thinking this will be fun. Yet what do I find? They threw in a ton of junk I don't need or want. I build massively within my expanded settlements and use a hell of a lot of scrap - "Cheat Room" gives me a roomful of foot lockers that provide over 65,000 of everything, so I can run this stuff over to my workbenches and they are set for life with ample supplies - one less thing to mess with - scrapping for crap. Yup - I use cheats - ones that allow unlimited carry weight, a built in jet-pack - no need for cumbersome PA, and only few others - these are to free up activities I simply do not enjoy in the game, and allows me to focus on MY mission in-game. What I DO NOT do is mess with my natural perks aquisition, and related - these remain as vanilla as the milkshakes I enjoy. And for good reasons based upon how the game was designed to function as opposed to changing these things up and then experiencing all manner of unforeseen issues - no thanx!.