I thought I would give Vortex a try from NMM and luckily I didnt jump in with both feet and change all my games over to vortex, I just tried Fallout4.
I read the tutorials and got all my fallout mods transferred from NMM to Vortex, enabling the mods is when problems started. i got numerous conflict warnings that never showed up in NMM and had to disable them again, going though one at a time. the mod load order was totally different from NMM (doesnt the transfer read the load order from NMM?) and i closed out and thought I would try another day.
As I followed the tutorial and had purged fallout from from NMM and cant just go back but now I cant even use Vortex either as when I started it up today it shows zero managed games! Its as thou iv never used it. Im logged in with my same account as before yet its as thou I never used it for fallout4. when I tell it to manage fallout4 again it now says no mods are found and it asks me for a deployment method again but will not accept the mods directory that it originally transferred all the mods into as it says it needs an empty directory, again.
Given Iv spend the best part of a day transferring fallout4 mods only to find its forgotten it all I dont think its worth risking doing again