If you are both CTDing right after the Bethesda logo, you most likely have a mod conflict. Two (or more) mods are either conflicting and/or one (or more) mods are reaching out for a dependency (like a needed patch to accommodate another mod) and you are crashing because of this.
In your mod manager (I'm presuming you're using one) disable (do NOT remove, just disable) all plugins except, Skyrim.esm, Update.esm, Dawnguard.esm, HearthFires.esm, and Unofficial Skyrim Special Edition Patch.esp. Now try to start your game. If it still crashes you have another issue. Possibly a corrupted download of the game or maybe just some files that didn't get properly updated. Try verifying your files through Steam.
Once your game is running, re-enable ten plug-ins (and any needed dependencies for those plug-ins) and try to launch again. When you start crashing again, you've got at least one of your conflicts narrowed down to those ten mods. Re-enable one at a time until you find it. Then read that mod's description thoroughly. Chances are good you'll find why that mod is causing the crash. Either through a conflict or a missing patch.
Some general advice for future mod-list building:
Here are some things you should consider when you add more than a handful of mods:
1) Mod Conflicts. If your Skyrim crashes to the destop (CTD) the moment the loading screen appears, it is very likely you have a mod conflict. Add only one or two mods at a time (and test them) to avoid having to plow through dozens of mods trying to find the one that's causing your game to crash. Also, RTFM. Mod authors WILL tell you what other mods (and/or types of mods) that their mod conflicts with. But that doesn't do you any good if you don't read that info before installing. Sometimes a patch is available to prevent a ctd from happening (or to prevent the mod from conflicting in some other way, like overwriting some scenery and causing weird in-game effects like floating trees and Mammoths raining from the sky. (Yes, that happens.)
2) Overwrites. When NMM installs mods, it will often stop and ask you a question like: "Do you want this mod to install (whatever) over (whatever) that already exists due to (whatever)? with about eight different options. Again, many mod authors will tell you what options to choose when installing their mod. When those instructions are not present, I've found it is usually best to answer "Yes to all" or the equivalent answer offered.
3) Load Order. Load order is literally the order that the mods are loaded into your game. This is just as important as overwrites. A "poor" load order will cause lots of issues ranging from weird in-game effects to CTDs. You can manually alter your load order in the "Plug-In" tab of NMM, but there's a better way. Download LOOT and install it. Point it at your directory where your mods are and let LOOT sort them. Not only will LOOT give you a better load order, but it will warn you about mods that need "cleaning" of dirty edits in them. And you can do that with TES5Edit. (or SSEEDIT for SE.) It's quite simple to use. However, be warned that some mods have INTENTIONAL dirty edits. Cleaning those mods will likely break them. How to know? Simple, the mod author will warn you if his/her mod has deliberate dirty edits.
4 SKSE. SKSE is short for "SKyrim Script Extender." Many popular mods use really cool and helpful interfaces like MCM (Mod Control Menus.) These mods require SKSE to function. Download SKSE and watch Gopher's video (linked in the description at the SKSE site) for what SKSE does exactly and how to install it. Don't worry, Gopher explains it clearly and concisely.