Installed Vortex, set it to manage Fallout 76. No problems there. Downloaded some mods, did the drag and drop of .zip files into the mods window, installed no problem. Enabled them, easy stuff. Deployed them and even went into settings and ticked the box to auto-deploy enabled mods (I have been reading through here before posting).
Launch the game through Vortex, takes longer than usual to load. And nothing. Game is the same as before. Just simple mods to highlight loot items, easy to see if it is working. Restarted game, no joy. Restarted laptop, nuttin.
On Windows 10, MSI laptop. Not getting any errors, nothing seems to conflict.
I am sure it is something silly and minor that I am missing, so I hope someone can just post a quick answer and call me a noob and move on.