The ENB's work well on FnV but beyond that this is probably better posted in the comments section of the ENB you downloaded.
I'm fairly certain if you ask around there'll be some people that will tell you your game won't/shouldn't run on Win7 or 8,
But I find the proof is in actaully playing unmodded. So how far into the game did you get. Megaton does'nt cut it, you need to make several cell transitions say head over to Meresti Station.
Also ENB isn't required for play...You should consider better textures over ENB.
Best thing now to do is uninstall it and get back in game to test it unmodded. If you can't even luanch the game now that ENB is in there, check to see that the game has the correct graphics card...Over in the same place as the INI files.
My experience with ENB on F03 has not been much better than yours. Honestly I think they just ported them over from there FNV playthrough's to F03 rather than building there palettes specifically for the F03 enviroment. You'll see what I mean when you get them working for both.
F03 I think looks fine with a weather mod project .....something cant remember same author of Climates of Tamrial Project Reality though.....His uses an END palette in a way to achieve the same effects.
Edited by gamefever, 14 February 2013 - 09:38 PM.