In general, if you haven't changed anything about your game and it suddenly stops working correctly you need to look to other causes: such as software updates to Windows, programming libraries such as ".Net", or hardware drivers. Older games eventually get dropped from product testing. It is also possible you are having problems with your hard drive. It never hurts to run "chkdsk" and an anti-virus scan.
FYI: If you recently had a Windows system update, you only have 10 days to revert to the previous version if you decide to choose that option.
How are you "zooming"? Mouse "scroll wheel" or keyboard "page up/down"? Have you tried the other method? Have you changed any hardware, such as plugging in a "game controller" which deactivates the keyboard?
We REALLY need to see a sorted "load order" (such as produced by "LOOT"); to include the main game and DLC files. (Screenshots don't work so well for the purpose.) With modded games its the sequence, not merely the list of mods, which is the cause of many problems. LOOT's sort gives a good first approximation, correcting the most obvious issues and is sufficient for most players. You can make minor adjustments to the order and tell LOOT how to remember them. It's in the on-line documentation under "Metadata". Instructions on how to copy it's list for posting are in the "How to ask for help" article, and "Checklist Item #11' entry in the wiki "Fallout NV Mod Conflict Troubleshooting" guide.
In the meantime, please see the 'Vanilla Load Order' entry in the 'First Timer Advice' section; and the 'Common Game Problems' section of the wiki "FNV General Mod Use Advice" article.
If the problem persists, then work through the ''Checklist' section of the wiki "Fallout NV Mod Conflict Troubleshooting" article.
I recommend anyone read the entire "FNV General Mod Use Advice" article to understand the differences between this game and others you may have experience with; especially if this is your first attempt to play a modded FNV or it's been more than a year since you last set it up. It is designed for someone who has never played a modded PC game before, so it tries to avoid making any assumptions, is kept "up-to-date", and covers years of "lessons learned". It is NOT a list of various mods to install that happen to work on the author's machine. It addresses fundamentals underlying how to get the basic game and mods to work together. At least 90% of everything I post in the "Technical Support" sub-forum is already in that article.
Edited by dubiousintent, 20 November 2020 - 12:31 PM.