I have fix for Steam version that worked for me. I launched ORIGIN Launched STEAM Selected Steam version of Mass Effect Andromeda in Origin select Settings In settings, go to game properties In properties go to Advanced Launch Options Go to the command line arguments I inserted the path to Frosty Mod manager executable I launch the game through Frosty Mod Manager my path to the Frosty Mod Manager looks like this for my installation, you will have to use your own path -C:\Users\shann\Documents\Mod Crap\MassEffect\Frosty\FrostyModManager EDIT: It will stop launching if mods are changed, to fix this just close Origin and launch again through the mod manager. Hope this works or helps