The problem solved ! I hope it will be useful ! 1. removed - Fallout4Custom.ini и Fallout4Prefs.ini (C:\Users\username\Documents\My Games\Fallout4 folder) 2. start the game - Fallout4.exe ( not Fallout4Launcher.exe!!!) , find out there is no CTD, exit the game.3. download this [spoiler=]https://www.nexusmods.com/fallout4/mods/102/ and used it to config the graphics settings instead of default "Fallout4Launcher.exe" , start the game, no CTD, exit. 4. add all mods that i need, played the game 2+ hours, not single fkn CTD was given. :cool: SUM - do not use the defaul Fallout4Launcher.exe if u have constant CTD problems.