Have the following load order, generated by BOSS, have the blood&mud files installed also. Oblivion.esm All Natural Base.esm Open Cities Resources.esm DA Run Fatigue.esm HorseCombatMaster.esm Unofficial Oblivion Patch.esp DLCShiveringIsles.esp Better Cities .esp All Natural.esp All Natural - SI.esp Immersive Interiors.esp Immersive Interiors - Lights Addon.esp 300_Combat Sounds.esp All Natural - Real Lights.esp WindowLightingSystem.esp Book Jackets Oblivion.esp ClocksOfCyrodiil.esp ImprovedSigns.esp RAEVWD New Sheoth.esp moDem's City Life.esp Crowded Cities 15.esp Crowded Roads 15.esp DropLitTorchOBSE.esp Get Wet.esp Adonnays Classical Weaponry.esp Adonnays Elven Weaponry.esp RealSwords - Argonian LO-NPC.esp RealSwords - Argonian LO.esp RealSwords - Khajiit LO-NPC v1.3.esp RealSwords - Khajiit LO v1.3.esp RealSwords - Orc LO v1.0.esp RealSwords - Orc LO-NPC v1.0.esp RealSwords - Redguard LO-NPC.esp RealSwords - Redguard LO.esp Cyrodiil transportation network 1.3.esp 300 Regal Imperial City 2.esp Jagnot- Imperial City Library V1.3.esp LetThePeopleDrink.esp za_bankmod.esp Open Cities New Sheoth.esp Open Cities Outer Districts.esp Open Cities Reborn.esp Visually Realistic Lava.esp Exterior Actors Have Torches 1.3 CT.esp HelmetFOV.esp ImmersiveHealthIndication.esp moremerchantmoneyv1.1.esp P1DkeyChain.esp PersuasionOverhaul.esp RealisticFatigue.esp More Capacity Encumbrance with Fatigue.esp DA Fatigued Running.esp DA ReducedBackwardsRunningSpeed.esp DA Sprint.esp Deadly Reflex 6 - Timed Block with no damage or durability changes.esp Mounted_Spellcasting_Deadly_Reflex_Compatible.esp DRSplatter.esp Kobu's Character Advancement System.esp ElaborateEyes.esp [GFX]_Initial_Glow-all.esp DeadlyReflex 6 - Combat Moves.esp All Natural - Indoor Weather Filter For Mods.esp It's been a while since I installed and played, but other than updating deadly reflexes and obse I haven't changed my mod list, and it used to work!