Good luck finding the culprit. I would suggest (and not without dread), uninstalling, permanetly deleting the mods from NMM, reinstalling the game, installing the smaller mods (like weapons, armors, important mods like racemenu, HDT physics, etc. ) and install mods like HD textures, enbs, additional homes and sites after starting the game and making a clean save. Reason I say this is these can be extremely taxing on the game and it will help you allot in finding the culprit. Also in case you haven't done it, make the necessary changes to you SKSE.ini file to enable the built in memory patch. Video on youtube to help you do it.
I've been playing with about 120-150 mods (allot of them are Sexlab :devil: ) and played for some time with very little crashes (once or twice in about 12 hour period). Got a new laptop, installed again, played about 4 hours not a single crash. Realized while searching for new mods that I had several mods that were extremely outdated, oops. Update 4 mods, played 10 minutes, bamm, constant crashing ( by crashing I mean stuck at load screen forever) every few minutes. Checked load order and dependencies with Loot (no problems), ran FNIS, nothing changed. Now stuck in breezehome. Can's walk out the door, can't COC anywhere but inside whiterun stables (worked perfectly), leave stables, bamm stuck at load screen forever, again. Even checked save game cleaner "no orphan scripts detected" (CRAP). Tried bout everything except the 1 thing I know will fix it, just sucks to do it, Delete and start over without the newer mod versions. Asus GL703VM-WB71 17.3" 120Hz screen I7 7700HQ 2.8 Ghz (3.8 Ghz Turbo) 16 GB DDR 4 Geforce GTX 1060 6 GB DDR 5 Samsung 860 EVO M.2 2280 250 GB (windows drive) Samsung 860 Pro SSD 500 GB (Games) Windows 10 Pro 64 Bit