The only bug (besides of course your usual Bethesda floating items and clipping bodies) that I have encountered was right after I took the elevator out of Vault 111 my character was stuck to the elevator. I couldn't open my Pipboy, I couldn't zoom out to third person, hell even enabling no-clip mode via the console didn't let me move. Turns out I had to alt-tab to force the game into the options menu so I could save, quit out, then load that save and I could move freely, but it didn't even change my name when I decided to change it before I left. Other than that I haven't experienced any CTD's or other gamebreaking bugs, but it does seems like Bethesda just doesn't give a s#*! anymore and leaves optimization up to the modders. So, I will patiently wait for there to be an Unofficial Fallout 4 patch to clean up all the dirty edits...