Hard to decide, maybe Phantasy Star Online, but that's more for the people than the game. I love all the Final Fantasy games I've played (7 to 12, excluding 11), Borderlands, Morrowind/Oblivion/Skyrim and the Fable series
And, yes, they do! Oh well, it's important. Hopefully it just means everyone will be well rested and ready for "gaming time" when FO4 comes out. (Whenever that might be!)