I hate to necro-bump but I'm having the same issue as OP almost verbatim. I want to update fallout 3 to 1.7 but running the patcher launches the game at the end, yet never actually updates. I can go to settings and see that it's still at 1.0.0.12. I've run it as admin, and uninstalled countless times, clearing out every mod in the fallout 3 directory. Without updating to 1.7 I can't use FOSE at all, which removes a few good mods from my list. This worked before and I had no problems. I made the mistake of installing a weather mod I didn't care for and had to uninstall the game, now I can't even get past the update so I can reinstall the mods. FOSE worked perfectly before, the only thing I did was uninstall, reinstall, and re-run the patch. Now it simply won't upgrade. edit: Well somehow I got it to work, I'm not sure exactly what I did. I removed one of the dll files from the fallout 3 folder so that it wouldn't run when it launched during the update. This wasn't even the first time I tried this but I did it right after a clean install, ran as admin, and removed pretty much everything from the fallout 3 folder that wasn't DLC, for some reason, it worked. This wasn't a problem before but I know if I ever uninstall again I'll have to deal with it, it felt like such a fluke that it suddenly worked.