My dudes, you can not imagine how f***ing long it took me, googleing for some form of fix to finaly, FINALY find people who have the same problem I have. And I think I might have found the solution (I can not verify this yet because bethesda has just today graced us with another damn CreationClub patch which I unfortunatley downloaded, so I will have to wait until F4SE updates), but I think what is causing this for me is the mod "Lots more Settlers and Enemies", which I only used because it is a required mod for the fantastic "Immersive Wastelanders" mod. After you wonderful people pushed me into the "it's NPC mods" direction, I finaly stumbled upon this being a known issue with LMSE and the author of Imemrsive Wastelanders provided a "fix" in his comment section. The dependency between IW and LMSE is only related to some face and hair assets. To keep IW working while also removing the stuttering and freezing issues caused by LMSE, you have to remove the NPCs added to the leveld lists by the mod with FO4Edit (a tutorial for that is provided in IW's comment). I so hope that this is solving the issue for me, because belive you me, I did f*#@ign EVERYTHING. Ini tweaks, mods reducing shadow quality, even the f***ing hour long process involved in using the Texture Optimization mod and it all did jack s***. If this realy solves the problem for me, i will celebrate. If this helps (or not, either way) I will come back to you guys. Seeing as some time has passed since you last talked here, maybe you also found this solution on your own (or found another one). Hopefuly you're reading this. Cheers, mates! Edit: I also just found out that apparently there is a complete rework of the Supermutant Redux mod in the works which will hopefully fix the stutter issues caused by that mod. I hope that comes soon, because Supermutant Redux truely is a must have.