I've been experiencing this a lot the last few days, mostly on fast travel, but it got to the point where I couldn't "continue". After looking at the size of my saves folder, I started quick saving. Reverting back to full saves and I haven't had a CTD for fast travel. I had the mechanist bug tonight and quit, but the game wouldn't load in "continue". Constant CTD as soon as the save loaded. So after checking a few things, I loaded a save outside the mechanists lair. All good. Then I started loading my saves in order, all good. I always save just before I quit as habit, so I had 2 saves within seconds of each other-mine and the "Exit" save. Mine loads fine, CTD on the exit save every time. It's only happened today, but the saves made by the game could be your issue. Try to Load your last manual save. Save manually often. Not quick save either.