I am having a similar issue. I can tell you one thing about your issue first. You should only have one of the 'fixer' mods, I'm pretty sure. Whichever one is most relevant to the version of the game you are currently playing. My situation, I am playing the game with a number of mods. Nothing too outlandish. The biggest ones are 5e spells, CYS (which I only use to change stats to reflect ability scores I rolled for my PC and party members), and Hexblade. Everything was working just fine. Even after Patch 1 came out. Suddenly, just now I updated the Hexblade and 5e spells mod and when I try to start the game it crashes before I can even click on continue. When the game reloads I have to go through the terms and gamma setting again. When I get back to the menu and select continue, the game tells me that such and such mods have been disabled and asks if I want to continue without them. None of the mods it says were disabled were the ones I just updated. Plus, Vortex still shows that all my mods are still enabled. What's going on? So... the game is telling me mods a, b, c, etc are now disabled and asking if I want to continue without them. Vortex is telling me they are still enabled. What happens to my game if I continue without them? Will my stats revert? Will items disappear? How much could it screw up my game? If it will screw it up a lot, how do I re-enable them when the game tells me they are disabled by vortex tells me they are enabled? HOW DO I FIX THIS??