I'm having issues too after updating Vortex. I don't get the failed to write load error anymore, but I can't load any of my characters, which I figured would happen. However every time I open Vortex now after the update, I get two messages in the upper right that pop up and say "Importing LSX" and "Reading Pak files, this will take awhile". I can start a brand new game, however no mods are present. I'm thinking of uninstalling all of my mods, uninstalling Vortex, updating the game again to vanilla, then reinstalling Vortex and then my mods. I'm hoping that works. The messages I keep getting are making me think something between Vortex and BG3 aren't communicating. Thanks for any help or suggestions.