[Deactivating / Uninstalling all mods question ... !]

i also have a question, is there any reason that after playing fallout 4 all my skyrm se mods became half disabled half uninstalled? at least according to vortex mods not plugins???

[SSE won't launch with an ENB]

yep i have a similar issue with the recent most enb binaries, follow it all to the letter but it just say loading cache plese wait, waiting does no good as i tried that but checking the task manager i can see the game is not responding, but i am using all the hdt mods not sure if conflict.