Same here :( I disabled all plugins for mods in the nexus and deleted my inis. I can now load old saves and start a new game without mods. When i set up my Fallout4Prefs.ini and Fallout4Custom.ini for modding with all mod plugins still disabeld in the nexus i get a ctd with my old save and new game. F4 1.5.157 (Steam) F4SE 0.1.13 NMM 0.61.20