Same problem here.. everytime I try to create a save, the game crash! I have a lot of mods installed (+100) but the game worked fine with all of those before and I didn't installed any new mods. I have just completed the main story line (I'm at "Throat of the World") and there is where I'm currently stuck! I have noticed that the size of my last saves are 10 mb. (I don't know if it can be revelant) I never had a problem with this version of Skyrim and I was blessing it for it's stabilty! If anyone have some question about my configuration or my mods, I will answer you. This is frustrating, I can't play anymore! EDIT: I play Skyrim SE with two different machines, desktop pc when I'm at home (more powerful and with graphics mods installed) and my laptop (without graphics mods and medium-low settings). Worked fine since now.. (game crash on both computers). So I think it's a save file problem. EDIT 2: This is my load order from LOOT:
0 0 Skyrim.esm
1 1 Update.esm
2 2 Dawnguard.esm
3 3 HearthFires.esm
4 4 Dragonborn.esm
5 5 Unofficial Skyrim Special Edition Patch.esp
6 6 Campfire.esm
7 7 Sneak Tools.esp
8 8 TERAArmors.esm
9 9 ApachiiHair.esm
10 a ApachiiHairFemales.esm
11 b Realistic Lighting Overhaul - Major City Interiors.esp
12 c Realistic Lighting Overhaul - Minor Cities and Town Interiors.esp
13 d iNeed.esp
14 e iNeed - Extended.esp
15 f Smilodon - Combat of Skyrim.esp
16 10 Smilodon - Realistic Damage.esp
17 11 Prometheus_No_snow_Under_the_roof.esp
18 12 WARZONES - SSE - Civil Unrest.esp
19 13 Realistic Lighting Overhaul - Major City Exteriors.esp
20 14 Realistic Lighting Overhaul - Dawnguard Interiors.esp
21 15 Book Covers Skyrim.esp
22 16 Reverb and Ambiance Overhaul - Skyrim.esp
23 17 Apophysis_DPM_SE.esp
24 18 Horse Storage.esp
25 19 When Vampires Attack.esp
26 1a Realistic AI Detection SE - Medium Interior, Medium Exterior.esp
27 1b Hothtrooper44_Armor_Ecksstra.esp
28 1c AsharaPrinceOfTheWoods.esp
29 1d NS_HuntingGroundsOutfit.esp
30 1e AncientDraugr.esp
31 1f Cassandra Frost Witch.esp
32 20 SkyrimIsWindy.esp
33 21 Immersive Jewelry.esp
34 22 SoundsofSkyrimComplete.esp
35 23 Merta Black Rose Armor.esp
36 24 Sotteta Necromancer Outfit.esp
37 25 Tembtra Thief Armor.esp
38 26 Book of UUNP Iron And Steel.esp
39 27 Realistic Lighting Overhaul - Dungeons.esp
40 28 OBIS SE.esp
41 29 Vivid WeathersSE.esp
42 2a icepenguinworldmapclassic.esp
43 2b Man Those Borders!.esp
44 2c skyBirds_SSE.esp
45 2d Hothtrooper44_ArmorCompilation.esp
46 2e JobsofSkyrim.esp
47 2f SoS_RLO_Major+MinorCityInteriors+Dungeons_Patch.esp
48 30 SimplyBiggerTreesSE.esp
49 31 Gwelda Red Riding Hood.esp
50 32 Gwelda Dawnguard Armor.esp
51 33 Celes Nightingale Armor.esp
52 34 imp_helm_legend.esp
53 35 Sneak Tools Vanilla Masks.esp
54 36 Sneak Tools Vanilla Hoods.esp
55 37 Cloaks.esp
56 38 WestWindAssault.esp
57 39 Blowing in the Wind SSE.esp
58 3a Immersive Patrols II.esp
59 3b Immersive Wenches.esp
60 3c Hunterborn.esp
61 3d Frostfall.esp
62 3e WetandCold.esp
63 3f Hunterborn - Campfire Patch.esp
64 40 Chesko_WearableLantern.esp
65 41 IB - All-in-One.esp
66 42 DragonboneBarbarianArmor.esp
67 43 Skyrim Flora Overhaul.esp
68 44 R18pn - Shanoa Armors.esp
69 45 Gwelda Armor Pack.esp
70 46 Ursine Armor Pack.esp
71 47 SL99Exchanger.esp
72 48 PrvtIRoyalArmory.esp
73 49 Blowing in the Wind - RLO Major City Exteriors Patch SSE.esp
74 4a Bijin Warmaidens.esp
75 4b Daedric Cults.esp
76 4c Equippable Tomes.esp
77 4d SL99Exchanger_Patch_Immersive Jewelry.esp
78 4e Blowing in the Wind - SMIM Merged All Patch SSE.esp
79 4f adventurerMashupComp.esp
80 50 TheLily.esp
81 51 Emfy Cleric Robes.esp
82 52 Sit Anywhere.esp
83 53 ExtendedStay.esp
84 54 Septims Have Weight - (0.005 Weight).esp
85 55 BecomeABard.esp
86 56 Visible Favorited Gear.esp
87 57 Hunterborn - Leather Tanning.esp
88 58 Hunterborn - Campfire Leather Tanning.esp
89 59 Halo's Poser.esp
90 5a ExtendedStay - Campfire Add-On.esp
91 5b Unique Uniques.esp
92 5c Skysan_GlassAW.esp
93 5d Better Harvesting.esp
94 5e KS Hairdo's.esp
95 5f True Eyes SE.esp
96 60 Immersive Wenches -KS hairs- Patch.esp
97 61 mihailesocenturion.esp
98 62 DustEffectsSSE.esp
99 63 dD - Enhanced Blood Main.esp
100 64 dD-Reduced Wound Size.esp
101 65 Footprints.esp
102 66 SkyrimIsWindy-BetterHarvest-Patch.esp
103 67 STAC.esp
104 68 Cloaks - Dawnguard.esp
105 69 Cloaks - USSEP Patch.esp
106 6a FaceMasksOfSkyrim.esp
107 6b ColovianNobleClothes.esp
108 6c Dr_Bandolier.esp
109 6d Merta Assassin Armor.esp
110 6e DarkerNights.esp
111 6f Realistic Lighting Overhaul - Weathers.esp
112 70 Realistic Lighting Overhaul - Dawnguard Weathers.esp
113 71 SoS_VividWeathers_Patch.esp
114 72 FNIS.esp
115 73 Populated Skyrim Prisons Cells.esp
116 74 Skysan_Stalhrim.esp
117 75 LightngDuringStorm.esp
118 76 SPTDiverseGuardsSkyrimSE.esp
119 77 Immersive Citizens - AI Overhaul.esp
120 78 RealisticWaterTwo.esp
121 79 RealisticWaterTwo - iNeed.esp
122 7a more idle markers.esp
123 7b Immersive Wenches -Immersive Citizens AI Overhaul Patch-.esp
124 7c Alternate Start - Live Another Life.esp
125 7d RAO - Alternate Start Patch.esp
EDIT 3: I have tried to clean my savegame with "FallrimTools" [http://www.nexusmods.com/skyrimspecialedition/mods/5031/?] without success. EDIT 4: I have deleted all the autosaves and the quicksave but the game still crash on save. EDIT 5: Ok I fixed it! First I have cleaned my savegame with "FallrimTools" [http://www.nexusmods.com/skyrimspecialedition/mods/5031/?], then I've cleaned dirty edit with SSEEdit [http://www.nexusmods.com/skyrimspecialedition/mods/164/?] following this video here: https://www.youtube.com/watch?v=fw3g_N1jcZQ I hope this help!