Noxxoma

Hello there, long time modder here (no expert). I had quite a few Fo4 mods installed and eveything was working fine but I hadnt played the game since 4 months ago (about). went on yesterday to find half my mods not working anymore. theyre still listed in the NMM but says theyre not working when i try to load the save. ive tried everything i know how to do with no avail. id really like to start playing again so some help would be much obliged