I'd look at several guides look at how they prepare the game for modding, watch guides on how the utilities such as wyrebash etc are used etc. Personally rather than slavishly following one particular guide, only to be disappointed as it ctds because a mod has updated since the guide was made, or installation error etc. I would decide on what you want out of Skyrim sse, and initially pick 30--40 mods to make this happen, reading guides and individual mod pages will give you an idea of which mods are going to be compatible.