I believe I am using the 4GB patcher. Graphics card is a GTX 1080, 16 gigs of ram, the processor is a core i7-9900k. ENB worked fine when I used it for New California, but that could be because the map's smaller. Wasn't running Nevada Skies then, so that might have something to do with it as well. Current theory is that it's too much to render. Going to attempt the enbseries download and see how that changes things. Might also try disabling Nevada Skies. Thanks again for the response - will update with what works ASAP. EDIT: After downloading the ESM and following guides shared, game now works. Thank you again.