First things first, it appears our fellow nexus user never achieved to make mods work, meaning the save cannot have been corrupted by mods. Starting all over again is likely to provide no benefit at all on this matter. About the original problem. I now encounter a similar issue, though mods used to work perfectly fine for me until today. What did I change then? Well I did not make any change in my installed mods (that have been running smoothly for several days with any issue), but I did verify game cache integrity with Steam and updated NMM to it latest version. Now almost every mod is broken, doesn't work at all or behave in very odd ways. Reinstalling NMM didn't change anything, reinstalling mods using NMM didn't change anything and even manually reinstalling mods didn't fix the problem. I also tried to check my .ini files, didn't change anything. I see two possibilities: - Verifying game cache integrity breaks mods in such way it is impossible to fix. - NMM update did something that corrupted installed mods. Anyway, considering I have a similar issue (and yours seems to be happening at the exact same time) I believe it is unrelated to mods and most likely to be out of our hands. You are right, mods have never worked for me. Thanks for the input. I've been looking around online for similar issues and other people believe that the latest update to Fallout 4 breaks mods.