I am having the same issue and it seems to be related to the bloom feature, and adaptation just makes it worse. Here is a forum post with some other people having a similar issue http://enbseries.enbdev.com/forum/viewtopic.php?f=21&t=1652 Here is a mod that fixes their particular instance of it with the leather backpack on Willow http://newvegas.nexusmods.com/mods/50998//? If you find a fix please let me know!