Using a pretty basic Gateway Desktop Computer with AMD Dual-Core E1-1500 APU Radeon HD 7310 Graphics, 500GB Hard Drive, and 6GB DDR3 Memory I can run a MAXIMUM of 255 Mods at the same time. Even one more than 255 causes Nexus Mod Manager to tell me Skyrim cannot handle any more than 255 and NMM is correct, Skyrim WILL not play any more than 255. That being said I am speaking from personal experience. Others might have more mods caused by a better computer or something but as far as I can tell... 255 is the max amount of Mods for Skyrim at any given time.
