First off, I am not using a mod manager, because I basically trust myself to do the work on my own. Having said that, I did make a backup of my data directory before modding.. These are the edits I used: Documents/My Games/Fallout 4/Fallout4.ini [Archive] sResourceDataDirsFinal=STRINGS\, TEXTURES\, MUSIC\, SOUND\, INTERFACE\, MESHES\, PROGRAMS\, MATERIALS\, LODSETTINGS\, VIS\, MISC\, SCRIPTS\, SHADERSFX\ Documents/My Games/Fallout 4/Fallout4Prefs.ini [Launcher] bEnableFileSelection=1 Documents/My Games/Fallout 4/Fallout4Custom.ini [Archive] bInvalidateOlderFiles=1sResourceDataDirsFinal= C:/Users/[YourUsername]/AppData/Local/Fallout4/plugins.txt # This file is used by Fallout4 to keep track of your downloaded content.# Please do not modify this file.Fallout4.esm*CBBE.esp*ReGrowth V4.esp*Workshop_Planters.esp*Any Other Mods.esp This file should not be read only, and you need to enter an * before any non official mods. I manually downloaded all the mods I used, copied them into my Fallout4/data directory. No issues