I think it has something to do inherently with 1.6 I just came back from overseas so I just updated to 1.6 last night. I didn't have many mods installed as I stopped playing and was using test characters for modding work. After updating, and getting the new SKSE etc. I find my game is crashing on launch. It crashes in the default launcher. It tries to detect my graphics settings and crashes. I tried deleting the old .ini files and that doesn't work. Clicking Play and then Play the game, doesn't work, it crashes with no indication. Trying to launch through the SKSE launcher doesn't work either. It's simply not going. I'm using the latest NVIDIA drivers that were available before 1.6, and I successfully played 1.5.+ with. I checked the Steam forums and this is a common issue to warrant a sticky. As far as it's known, NOONE knows what's the problem, but appears to be linked to possibly the .exe file. Other than completely uninstalling and reinstalling, it's suggested to do a system restore to a previous version of the game .exe file.