I just finished fixing almost the same issue, except with a different file. I also have the Eyes of Perfection mod, but that file wasn't the culprit for me. It was roofmetal03_d.dds but I'm not sure what mod it was from. So for me, my game didn't crash until those textures were loaded in upon going into a certain part of the map. I suspect that your issue is exactly the same except that your save was in a location where the texture had to be loaded in upon loading in (either you or an NPC near you had brown eyes). But basically my situation was exactly the same as yours. Including that I discovered it after reading about textures causing crashes on the forums and the way I fixed it. Here's the methodology I used, in case people experiencing a similar issue wish to replicate it: 1. With the textures removed, I went to the location that caused my game to CTD and saved. That way I could load the game and immediately know. 2. 30 at a time, I put the files back in and started my game. If that batch didn't cause a CTD they would be placed in the "safe" folder. 3. The second batch crashed my game and they were placed in an "unsafe" folder. 4. The third and final batch did not crash my game and were placed into the "safe" folder. 4. I started placing the "unsafe" files in at larger amounts, then smaller and smaller amounts, until I had narrowed down which file had the issue. So if you want to repeat it: 1. For me, this didn't CTD on loading the save, but instead in a specific region of the map. What I did was I removed the "Textures" folder and went to the area that I CTD, and saved my game there so I could load it up and know right away if it's still an issue. 2. Narrow down which folder in "Textures" is causing the issue. No need to do them one at a time at first. 3. Narrow down which files in that folder are causing the issue. Start with large batches of files and narrow them down. Put the "safe" files in a separate folder and don't load them in so they don't get mixed up. I'm still unsure about what causes the issue, though. What's different about this texture that crashes the game? If anyone finds out, please do share.