I've been getting back into New Vegas for the past few days by preparing it for a heavily-modded run on my relatively-new PC, and I've had to deal with all the ins-and-outs before, but I haven't seen anything like this. See, Mod Organiser's affiliate programs (LOOT, Wrye Flash) refuse to work correctly whenever there is are any active files containing NVSE plugins. I don't know why this is happening, I've searched for the past 5 hours for an answer, and I'm juts tired now. So tired, perhaps, that there's a completely logical resolution to this all that simply eludes me in my exhausted stammering. I've tried reinstalling all the affiliate programs (eg, NVSE, Wrye Flash), reinstalling Mod Organiser (and even reverting to older, more stable versions) verifying the integrity of the game cache... I'm at the end of my rope now, so I'll just have to ask you guys if you can help. Thanks.