I have tried the following with the following results: Fallout4Prefs.ini section marked [Launcher]: bEnableFileSelection=1 - no change Fallout4Custom.ini: [Archive]bInvalidateOlderFiles=1sResourceDataDirsFinal= - CTD upon load of new/save game (even without any mods loaded with NMM) Fallout4.ini: repalce the line sResourceDataDirsFinal=STRINGS\ (under the [Archive] section), with:sResourceDataDirsFinal=STRINGS\, TEXTURES\, MUSIC\, SOUND\, INTERFACE\, MESHES\, PROGRAMS\, MATERIALS\, LODSETTINGS\, VIS\, MISC\, SCRIPTS\, SHADERSFX\ - CTD upon load of new/save game (even without any mods loaded with NMM)(this change was from IGN.com, although i have not seen anyone else say to do this) Reinstalling Fallout 4 via Steam - no change Verified that Plugins.TXT has an asterisks (*) in front of all activated ESP's. --------------------------------------------------------------------------------------------------I have tried the above in all combinations with and without mods and with and without F4SE. I have also sorted with LOOT.When mods are installed and enabled via NMM and when I don't receive a CTD, load times in game are increased but don't take affect.The only Mods i can get to work are "Scrap Everything" and "Modern Weapons." "Full Dialogue Interface" will display full dialogue, but only in the vanilla format (the up/down/left/right arrows).if anyone wants me to upload a crash dump file i will need them to tell me where it is as i would not know. Is there anyone that could help me? System:Fallout 4 version is whatever Steam says is current as of 24JAN2018 - game installed on E:\Windows 8.1 64-bitAMD FX-8350ASUS STRIX NVIDIA GTX 980-ti32GB Ram