Brand new to pc gaming but I spent some time researching mods before installing so I'm not completely ignorant. Just mostly :smile: The situation: built a new pc (G4560, 16GB 3733 mhz ram, Asus strix 1060 6gb) , installed win 10 (home not pro), steam, fallout 4, NMM, LOOT, etc. The game runs great in vanilla. Followed Gophers tutorials meticulously on installing F4SE. Game runs from F4SE launcher no problem. Followed another install vid on FO4 configuration tool (installed on desktop, not as launcher, wasn't sure if it would conflict with F4SE launcher) game runs with it no problem. Back to Gopher for Shadow boost install. I believe it is running fine, but my test character is still in the vault and I can't get the game to budge from 60 fps so I'm not entirely sure, but I think it is. Here's where it goes sideways... foolishly I got cocky and downloaded/installed (with NMM) Awkcr, Unofficial FO4 Patch, Full dialog interface, FAR, insignificant object remover and optimized vanilla textures back to back without running the game to be sure they are functioning properly. Now when I load my save game with mods installed it goes to the load screen for the normal amount of time but instead of opening the game it crashes to desktop with no error message. If I try to start a new game with mods it starts to load (little vault emblem in lower right is doing its thing) and just stays that way until I give up and close with task manager. If I uninstall (not delete) the mods the game runs great from save game or new start. What I've tried so far: verified game thru steam (it found and added 1 missing file), made sure NMM, FO4, etc are running in admin. mode, tried running the game with various mod combinations, uninstalled avast as I heard it can conflict with FO4, as well as poking thru every dialog box I can find looking for... I don't know what... all no joy. I realize the simple solution would be to uninstall, delete and re-download, but I'm more interested in finding out why this is happening so I don't replicate it in the future. LOOT is happy with load order, NMM installed and is happy with the mods but obviously FO4 is not happy. Any help would be greatly appreciated. Thanks in advance.