I'm running A Mac Pro 2.8GHZ , 12GIG of RAM, Radeon 7950 3GIG Bootcamp /Windows 10. I never had this problem with the vanilla game, when I enter Cabot House (sitting down with Mr. Cabot), Corvega Car Plant (tunnel, stair leading to boss), Institute (enter chamber to father and fake son, talking with department heads) I get a hard computer crash shut down and sometime CTD. I don't know if its a mod causing this or bad frame rate with Fallout 4. I'm running the latest Horizon mod, an having problem creating Call bot, says recipe Call Bot locked? anyone know how to unlock it? sometimes I don't care about going to the institute, storyline is so boring to play over and over again.