i had the same problem about the corrupt saves but i somehow fixed it but now of course its another problem, its in the boston area where you try to find valentine in train tunnels. its like instant ctd in and out around the swan area. But for the save corrupt, mine was corrupting because Vortex was actually disabling my mods and basically reactivating them. i was sorta over the mod limit but now im at 234 active mods and 45 lights. also make sure you make the files light if it could be light. Because that was also why my esm slots were getting taken up. But any help? do i have to do the classic activate and disable? i kinda dont want to because i already did that to fix the corrupt saves. also prior to the corrupt saves ny fallout 4 wouldnt even start up it would straight crash. but i fixed it, it was the better locational mod and there was a weaponsmith plug in that was also crashing my game. i deleted that and now my game works fine now just not in the boston area. im finding to notice im getting one problem after the other and i fixed the majority on my own and looking at similar topics to fix my problems. i use loot to sort the load order and cleaned the required mods that need to be cleaned. got the correct mods and patches and plug ins to make my game run smooth. im so in love with this game and i legit try my best and when theres a problem i cant help to pick at it to make it work. ive done so much good so far aiming to get the perfect playthrough, my game runs good having heavy mods on and it crashes rarely when i aim at an enemy and just the ctd around the boston area.