This is part mod troubleshooting, part "general mod talk". I've read on the Bethesda Skyrim forums that, if we want to play without a mod, we have to load a save made before the mod was activated. Are there issues with loading a save without the mods that were active when it was saved? Is it possible to continue playing with those save files while the mods are deactivated or uninstalled without any issues? I ask because my Populated Cities mod currently exists as two files: an ESM and an ESP. The mod adds a plethora of actors, leveled actor and item lists, outfits, and places actor, furniture, xmarker, and idlemarker references throughout each city, along with a couple scripts and custom AI packages. I eventually want to combine the two into a single ESP, or rebuild it as a single ESP. I want to know if this can cause issues to save files created while using the ESM and ESP version.