I know it's too late for leaving a comment here, but maybe I will help someone who (just like me) faced this particular problem. Absolutely every hostile creature in game ignored me until i shot first. I almost gave up on game, cause none of the solutions from other similar threads on reddit and other sites had any success. I discovered it randomly myself and it worked for me. So, basicly, as I presume, one of my sex mod put my character in captive faction, which is friendly to any creature. To fix that you need to open console and type "player.removefromfaction 0003e0c8", and you will be good to go.