It is too bad this post was from so long ago. I have almost 200 plug-ins and 200 mods loaded and it works reasonably well. I use VORTEX to watch over it all. It does a decent job of detecting conflicts and gives you a reasonable way to remanage them. I have still started over about 3 times, but mostly because I kept changing the mods 1/2 way through. lol It's not a perfect system, but neither is Oblivion by any cry. I still get the memory cannot read error, so I am certain I am missing something or something needs writing. I think that after more than 10 years of playing this game and still loving it, I can deal with a few problems. The changes I have made have created a whole new gaming experience for me here. I also use a lot of console commands to get around a few things. One thing I did do was to write a script that boosts my companions' stats so that they don't go unconscious so often. I kicked up their health to around 90,000. They don't hit 0 often. I do have to execute the script every time I: level sleep stop/start the game and when they leave (as they often do) and come back in their original garb Hope you got your situation fixed and had fun!!!