I've never heard this one (and I do it all the time). Are you sure you didn't mistake it with something like 'don't keep saving over the same save game slot'? Because that will contribute to corrupt saves. If the situation has not really improved that much, and you feel the CTDs are still too frequent for your taste, the last thing that can be explored is a complete reinstall of the game and (a more modest number of) mods. If you do this, I recommend you use a mod manger like the 'Mod Organizer', which won't install mods directly into the game data folder (so if, by chance, you ever need to do another 'full reinstall', you actually won't need to 'reinstall' the game because there will be no loose files in the game data folder, if you installed all your mods via the MO). You can list the mods you'd like to 'add back' to the new installation, and I am sure many users will drop by to let you know their own experiences with such mods. Aside from that, I can't think of anything else to try. So how will this work with NMM & Steam Workshop mods? I've never heard of this Mod Organizer before....