Whats wrong with it being installed to program files???

[Smooov516]

When I dowloaded the archive invalidation program i noticed it said that Fallout 3 may have problems running because it was installed to the programs folder.I havnt had any problems untill now since I have been downloading more mods.Now for some reason my computer is having problems crashing when I run into too many NPCs.

 

This started happenng when I installed a Hi res landscape,Sharing and caring mod with Sasha and another companion using the vannila system,Maria cruz and the latest FOOK.I use the MMF increase spawn mod (with fook plugin)which didnt cause me a problem in the past but it does now.I think its between that and my companions because I took out the landscape and things got a little better but I cant even travel to pen station east where the Brotherhood is defending the whitehouse it just crashes when during loading or when I get close to the encounter.It crashes sometimes for the washington momument.I also use the Raider Merc expanded mod which adds in more armor,weapons,female merc/regulators and has a plug in for the MMF mod but not the new beta version.Well my main question is what are the limitations of having it installed in program files and Can I just Select the Fallout 3 folder and put it some where else to avoid them?? Thanks

 

Also in FOOK I have noticed that super mutants sometimes dont use thier weapons and sometimes didnt even have the right ammo for them.I will have a video showing it here later.It will be named FOOK you.