Mod detection possible?

[Pixellc]

I'm curious, would it ever be possible to create a mod that detects if other players are using mods, like what some of the Souls games have? I see a lot of mods that I would really argue are just cheating, and if possible I'd like to avoid playing with people using mods like these. Like, it's one thing if you double dipped and want your old charms back, or if you just wanna screw around in singleplayer, but if you're giving yourself Rainbow Spiribirds at the start of every quest, or having all damage buff items consolidated into Might Seeds that last 20 minutes, or even having items just automatically use themselves when you need them to with no animation or risk, that's where I draw the line.