Using more than one collection with FNV. Is it viable?

[seweryn]

So I found more than one collection I like.

One is changing faces, the other changing the environment, another is adding quests, and the other is totally changing the game aka total overhaul.

I wonder, is it possible to use more than one collection?

I personally like adding tons of armor, and weapons to my game but I found that there is ton of work getting some mods to work with one another.

So can it be done using more than one collection?

Thanks for the info,

P.S.

I am asking specifically for NV since I know this game can be a little tricky when it comes to modding. It feels like playing oblivion again.