What kinds of weapons/ammo patches are safe to install mid-modded playthrough?

[kplusa]

How far can you go with weapon mod patches from FO4edit without breaking the game or mod?

I can understand that it's not safe to remove or possibly add a weapon mod in an existing playthrough to/from a leveled list (injection).  Or to remove an attachment from the game that is currently equipped on a weapon in your inventory.

For example, is it safe to totally change the name of a weapon in your inventory or the one you have equipped? Can I change its ammo to something from Munitions on FO4edit?

How about removing a scope attachment from the game that is currently attached to a weapon in a container in a settlement?