Merging Compatibility Files

[Kuwbara101]

I'm not exactly a pro at modding but I do know that you can merge certain mods together. Like I have Crazylion's replaces for the Blade of woe,the ebony blade, and chillrend and all of Zerofrost's armors (Manly for Legacy's armory.) merging their esps together was fine. I am mainly wondering about files like Expanded Towns and Cities Patches, Audio Overhaul for Skyrim's patches and any compatibility patches in general. That way my esp load shrinks a bit from like 214 to like 198.

P.s Rs Children have patches on a separate mod page as well. I merged those and it worked that's why I am curious about these bigger mods.

Any info or advice would be appreciated.

Thanks people.