Cannot pick up quest items in skyrim

[panrope]

Hey everyone.

Kind of stuck here. I have a level 43 character in skyrim and recently my game decided that i wouldn't be able to find quest items. For example. I am retrieving one of the fragments of Wuuthrad and i work my way through Orotheim to get the fragment. It is supposed to be in the chest at the end (mission marker hovered above it) however when I open the chest i cannot take the fragment. I have the same problem with The Pale Lady Quest, and The Eldergleam quest where i have to grab nettlebane off of a hagraven in the eldergleam and the pale blade off of the khajiit guy in the pale lady. I cannot see the item in the game. If i console the item in and complete the quest without finishing that part of the quest the quest remains in my questlist. Does anybody know of a fix for this? This started happening before i got update 1.5 and continued after 1.5. Any help is appreciated. Thanks!